Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta‐analysis. Issue 3 (10th July 2016)

• Record Type: Journal Article
• Authors: Kong, Lingde; Cao, Junming; Zhang, Yingze; Ding, Wenyuan; Shen, Yong
• Is Part Of: International wound journal. Volume 14:Issue 3(2017)
• Page Start: 529
• Page End: 536
• Publication Date: 2016-07-10
• Subjects: Meta‐analysis -- Periprosthetic joint infection -- Risk factor -- Systematic review -- Total joint arthroplasty; Wounds and injuries -- Treatment -- Periodicals; Wounds and injuries -- Periodicals; Wound healing -- Periodicals; 617.1005
• DOI: 10.1111/iwj.12640
• Languages: English
• ISSNs: 1742-4801

Abstract

Abstract: To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical‐related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.17–−0.03), obesity (OR, 1·54; 95% CI, 1·25–1·90), alcohol abuse (OR, 1·88; 95% CI, 1·32–2·68), American Society of Anesthesiologists (ASA) scale > 2 (OR, 2·06; 95% CI, 1·77–2·39), operative time (SMD, 0·49; 95% CI, 0·19–0·78), drain usage (OR, 0·36; 95% CI, 0·18–0·74), diabetes mellitus (OR, 1·58; 95% CI, 1·37–1·81), urinary tract infection (OR, 1·53; 95% CI, 1.09–2.16) and rheumatoid arthritis (OR, 1·57; 95% CI, 1·30–1·88). Among these risk factors, ASA score > 2 was a high risk factor, and drain usage was a protective factor. There was positive evidence for some factors that could be used to prevent the onset of infection after TJA.