Matrix‐Embedded Cells: Matrix‐Embedded Endothelial Cells Attain a Progenitor‐Like Phenotype (Adv. Biosys. 9/2017). Issue 9 (11th September 2017)

• Record Type: Journal Article
• Authors: Abraham, Eytan; Gadish, Or; Franses, Joseph W.; Chitalia, Vipul C.; Artzi, Natalie; Edelman, Elazer R.
• Is Part Of: Advanced biosystems. Volume 1 :Issue 9 (2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-09-11
• Subjects: 3D -- endothelial cells -- endothelial progenitor cells -- matrix embedding -- scaffolds; Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; Biological Science Disciplines; Periodicals; Periodicals; 660.6
• DOI: 10.1002/adbi.201770069
• Languages: English
• ISSNs: 2366-7478

Abstract

Abstract : Natalie Artzi and co‐workers describe how matrix‐embedded endothelial cells (MEEC) attain a progenitor‐like phenotype as defined by comparisons of secretome, phenotype, and genetic fingerprint of MEECs with that of endothelial progenitor cells, in article number1700057 . The cover shows MEECs (green) wrapping around the denatured collagen structure (red) of the matrix, recapitulating in vivo endothelial structure much more closely than endothelial cells grown on 2D surfaces.