Use of Tolvaptan in a Patient With Palliated Congenital Heart Disease. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Chakravarti, Sujata; Busovsky-McNeal, Melissa
• Is Part Of: World journal for pediatric & congenital heart surgery. Volume 9:Issue 1(2018)
• Page Start: 114
• Page End: 116
• Publication Date: 2018-01
• Subjects: congenital heart disease -- heart failure -- pharmacology -- preoperative care; Pediatric cardiology -- Periodicals; Congenital heart disease in children -- Periodicals; Heart -- Abnormalities -- Surgery -- Periodicals; Heart -- Surgery -- Periodicals; Heart Defects, Congenital -- surgery -- Periodicals; Cardiac Surgical Procedures -- Periodicals; Child -- Periodicals; Adult -- Periodicals; 618.9212
• DOI: 10.1177/2150135116664319
• Languages: English
• ISSNs: 2150-1351

Abstract

Heart failure is a common problem in the ever growing population of patients with palliated congenital heart disease. It is frequently complicated by hyponatremia that has been associated with increased morbidity and mortality. Tolvaptan is a vasopressin receptor antagonist that has been effective in improving hyponatremia and congestive symptoms in adults with chronic heart failure. We describe the short-term use of tolvaptan to treat hyponatremic hypervolemia in an adolescent patient with chronic heart failure in the setting of palliated congenital heart disease prior to definitive surgical intervention. In this case, the patient had improvement in hyponatremia and a decrease in body weight, without any adverse effects.