The Concise Guide to PHARMACOLOGY 2013/14: Catalytic Receptors. (17th December 2013)

• Record Type: Journal Article
• Authors: Alexander, Stephen P.H.; Benson, Helen E.; Faccenda, Elena; Pawson, Adam J.; Sharman, Joanna L.; Spedding, Michael; Peters, John A.; Harmar, Anthony J.
• Is Part Of: British journal of pharmacology. Volume 170:Number 8(2013:Dec.)
• Page Start: 1676
• Page End: 1705
• Publication Date: 2013-12-17
• Subjects: Pharmacology -- Periodicals; Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1111/bph.12449
• Languages: English
• ISSNs: 0007-1188

Abstract

Abstract: The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org ), which provides more detailed views of target and ligand properties. The full contents can be found athttp://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full . Catalytic receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein‐coupled receptors, ligand‐gated ion channels, ion channels, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the websitewww.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC‐IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR‐DB and the Guide to Receptors and Channels, providing a permanent, citable, point‐in‐time record that will survive database updates.