Malignant Mixed Epithelial and Stromal Tumor of the Kidney With 2 Simultaneous Renal Carcinomas in a Male Patient: Case Report and Review of the Literature. (February 2018)

• Record Type: Journal Article
• Authors: Arriola, Aileen Grace P.; Taylor, Benjamin L.; Ma, Sophia; Malkowicz, S. Bruce; Lal, Priti
• Is Part Of: International journal of surgical pathology. Volume 26:Number 1(2018)
• Page Start: 56
• Page End: 63
• Publication Date: 2018-02
• Subjects: malignant mixed epithelial and stromal tumor kidney; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/1066896917720032
• Languages: English
• ISSNs: 1066-8969

Abstract

The majority of mixed epithelial and stromal tumors (MEST) of the kidney are benign entities found in female patients. Malignant MEST of the kidney is an extremely rare entity that often behaves clinically similar to an undifferentiated sarcoma. We report a case of a malignant MEST with synchronous papillary and clear cell renal cell carcinomas (RCCs) in a 61-year-old Caucasian man who presented with an incidental finding of a left renal mass on workup for back pain. The patient underwent a left radical nephrectomy, with histopathology confirming a malignant MEST, intimately associated papillary RCC, and separate adjacent focus of clear cell RCC.