Readily Accessible and Predictable Naphthalene‐Based Two‐Photon Fluorophore with Full Visible‐Color Coverage. Issue 40 (18th August 2016)

• Record Type: Journal Article
• Authors: Koo, Ja Young; Heo, Cheol Ho; Shin, Young‐Hee; Kim, Dahahm; Lim, Chang Su; Cho, Bong Rae; Kim, Hwan Myung; Park, Seung Bum
• Is Part Of: Chemistry. Volume 22:Issue 40(2016)
• Page Start: 14166
• Page End: 14170
• Publication Date: 2016-08-18
• Subjects: acedan -- biosensors -- fluorescence -- hydrogen peroxide -- visible color; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201603496
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Herein we report 22 acedan‐derived, two‐photon fluorophores with synthetic feasibility and full coverage of visible wavelength emission. The emission wavelengths were predicted by computational analysis, which enabled us to visualize multicolor images by two‐photon excitation with single wavelength, and to design a turn‐on, two‐photon fluorescence sensor for endogenous H2 O2 in Raw 264.7 macrophage and rat brain hippocampus ex vivo. Abstract : Technicolor detector : Herein, 22 naphthalene‐based two‐photon fluorophores are reported. They are synthetically feasible and have a full coverage of visible color emission wavelengths, which were well‐predicted by computational analysis. A two‐photon fluorophore allows for the visualization of multicolor images by two‐photon excitation with a single wavelength and the rational design of a turn‐on, two‐photon fluorescent sensor for endogenous H2 O2 in Raw 264.7 macrophage and rat brain hippocampus, ex vivo.