Tor-dependent post-transcriptional regulation of autophagy: Implications for cancer therapeutics. (2nd September 2016) - Hu, Guowu
ABSTRACT: Paradoxically, both anticancer immunosurveillance and tumor progression have been associated with intact autophagy, which is regulated by the target of rapamycin (Tor1). Here, we describe the potential impact on the design of cancer therapeutics of a newly described highly conserved post-transcriptional mechanism whereby Tor regulates autophagy.