First- and second-order contrast sensitivity functions reveal disrupted visual processing following mild traumatic brain injury. (May 2016)

• Record Type: Journal Article
• Authors: Spiegel, Daniel P.; Reynaud, Alexandre; Ruiz, Tatiana; Laguë-Beauvais, Maude; Hess, Robert; Farivar, Reza
• Is Part Of: Vision research. Volume 122(2016)
• Page Start: 43
• Page End: 50
• Publication Date: 2016-05
• Subjects: Traumatic brain injury -- First order vision -- Second order vision -- Motion perception -- Contrast sensitivity; Vision -- Periodicals; 573.88
• DOI: 10.1016/j.visres.2016.03.004
• Languages: English
• ISSNs: 0042-6989

Abstract

Highlights: TBI patients have increased sensitivity for 1 st order motion stimuli. TBI patients have decreased sensitivity to contrast-defined 2 nd order stimuli. TBI patients have decreased sensitivity to orientation-defined 2 nd order stimuli. CSFs are shifted towards higher spatial frequencies in TBI patients. Abstract: Vision is disrupted by traumatic brain injury (TBI), with vision-related complaints being amongst the most common in this population. Based on the neural responses of early visual cortical areas, injury to the visual cortex would be predicted to affect both 1 st order and 2 nd order contrast sensitivity functions (CSFs)—the height and/or the cut-off of the CSF are expected to be affected by TBI. Previous studies have reported disruptions only in 2 nd order contrast sensitivity, but using a narrow range of parameters and divergent methodologies—no study has characterized the effect of TBI on the full CSF for both 1 st and 2 nd order stimuli. Such information is needed to properly understand the effect of TBI on contrast perception, which underlies all visual processing. Using a unified framework based on the quick contrast sensitivity function, we measured full CSFs for static and dynamic 1 st and 2 nd order stimuli. Our results provide a unique dataset showing alterations in sensitivity for both 1 st and 2 nd order visual stimuli. In particular, we show that TBI patients have increased sensitivity for 1 st order motion stimuli and decreased sensitivity to orientation-defined and contrast-defined 2 nd order stimuli. In addition, our data suggest that TBI patients' sensitivity for both 1 st order stimuli and 2 nd order contrast-defined stimuli is shifted towards higher spatial frequencies.