Comorbidity between idiopathic overactive bladder and chronic migraine. (March 2018)

• Record Type: Journal Article
• Authors: Ramos, Marta L; García-Cabo, Carmen; Leira, Rogelio; Domínguez, Clara; Pozo-Rosich, Patricia; Vila, Carme; Laínez, Miguel J; Pascual, Julio
• Is Part Of: Cephalalgia. Volume 38:Number 3(2018)
• Page Start: 581
• Page End: 584
• Publication Date: 2018-03
• Subjects: Calcitonin gene-related peptide -- chronic migraine -- comorbidity -- overactive bladder; Headache -- Periodicals; 616.8491
• DOI: 10.1177/0333102417690127
• Languages: English
• ISSNs: 0333-1024

Abstract

Objective: We tested whether overactive bladder (OAB) and chronic migraine (CM) could be comorbid. Patients and methods: CM women, aged 40–69 years, answered a validated OAB questionnaire. Prevalence data were compared with those reported in our country in the general population (GP) using the same questionnaire. Results: We interviewed 231 CM women. Eighty-four met OAB criteria. OAB prevalence in CM patients was significantly higher than that found in the GP (36.4% vs. 21.8% in the GP; p = 0.0001). There were 34 CM women aged 40–49 years (34.3% vs. 15.2%; p = 0.001), 35 aged 50–59 years (38.9% vs. 21.7%; p = 0.004) and 15 aged 60–69 years (35.7% vs. 24.5%; p = 0.15) meeting OAB criteria. Seventy-seven (33% vs. 9.9%; p = 0.002) needed more than eight micturitions/24 h, 61 (26.4% vs. 8.1%, p = 0.002) experienced nocturia and 43 (18.6% vs. 8.1%; p = 0.001) urinary incontinence. Conclusion: In this exploratory study, at least in women, OAB and CM are comorbid, which suggests shared mechanisms.