Acute gastrointestinal bleeding cases presenting to the emergency department are associated with age, sex and seasonal and circadian factors. Issue 1 (January 2017)

• Record Type: Journal Article
• Authors: Lenzen, Henrike; Musmann, Eliane; Kottas, Martina; Schönemeier, Bastian; Köhnlein, Thomas; Manns, Michael P.; Lankisch, Tim O.
• Is Part Of: European journal of gastroenterology & hepatology. Volume 29:Issue 1(2017:Jan.)
• Publication Date: 2017-01
• Subjects: gastrointestinal bleeding -- meteorological factor -- risk factors -- seasonal variation; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; Digestive organs -- Diseases; Liver -- Diseases; Periodicals; 616.33
• DOI: 10.1097/MEG.0000000000000752
• Languages: English
• ISSNs: 0954-691X

Abstract

Abstract : Background: Gastrointestinal bleeding (GIB) is one of the most common emergencies in gastroenterology. The aim of this study was to investigate the association between the incidence of GIB and seasonal, circadian and meteorological patterns in the emergency department (ED) of a tertiary hospital. Patients and methods: From January 2007 until December 2012, we retrospectively evaluated patients presenting to the ED with respect to the number and location of GIB, season, time of day and weather. Results: Of 45 458 patients, 578 (1.3%) presented with a GIB. Of these, 62.5% were men compared with 54.7% of all patients in the ED ( χ 2, P =0.0002). Patients with GIB were on average 4.4 years older than those without GIB (95% confidence interval 2.76–5.98, t -test, P <0.001). In addition, 304 (52.6%) patients had upper GIB and 138 (23.9%) had lower GIB. In total, 136 (23.5%) patients required no endoscopy because of initial laboratory and circulatory stability. In univariate analysis, meteorological parameters, including air temperature, cloud cover, relative humidity, vapour pressure, amount of precipitation, sunshine duration and snow height, were each associated with an increased risk of acute GIB (all P -values<0.05). In the 6-year study period, patients with GIB presented to the ED mainly during the winter months. Independent predictors of GIB on multivariate logistic regression were older age, male sex, season and daytime, all P less than 0.005. Emergency admissions during the night were associated with a 54 and 35% higher risk of GIB compared with daytime (8 a.m. to 4 p.m., P =0.0002) and late evening hours (4 p.m. to midnight, P =0.0142), respectively. Conclusion: Presentation of patients with acute GIB in the ED is age and sex specific and shows seasonal and circadian differences in distribution, with an increased incidence in winter months and during night-time. This should be considered when determining possible emergency endoscopic interventions and the availability of emergency endoscopy services. Abstract : Supplemental Digital Content is available in the text.