Surgical treatment of stage 2 medication-related osteonecrosis of the jaw compared to osteomyelitis. Issue 6 (2nd November 2018)

• Record Type: Journal Article
• Authors: Kang, Sang-Hoon; Won, Yu-Jin; Kim, Moon-Key
• Is Part Of: Cranio. Volume 36:Issue 6(2018)
• Page Start: 373
• Page End: 380
• Publication Date: 2018-11-02
• Subjects: MRONJ -- bisphosphonate -- osteonecrosis -- osteomyelitis -- surgical procedure; Temporomandibular joint disorders -- periodicals; Temporomandibular joint -- Diseases -- Periodicals; 617.51
• DOI: 10.1080/08869634.2017.1365413
• Languages: English
• ISSNs: 0886-9634

Abstract

Abstract: Objective: To compare the characteristics and outcomes of patients who underwent surgical treatment for stage 2 medication-related osteonecrosis of the jaw (MRONJ) versus osteomyelitis. Methods: This retrospective study compared the following variables in 73 patients with stage 2 MRONJ versus 89 patients with osteomyelitis: impaired wound healing after surgery, sex, age, the presence of actinomycosis, location of the jaw lesion, and involvement of the inferior alveolar nerve (IAN). Results: There were significant differences between the groups in age, sex, rates of impaired wound healing, actinomycosis, and the location (anterior/posterior) of the lesion. Impaired wound healing after surgical treatment in the stage 2 MRONJ group was associated with patient age. All patients with impaired wound healing after the initial surgery recovered fully after reoperation. Conclusions: These findings for surgical treatment of stage 2 MRONJ may help clinicians plan surgical treatment of MRONJ.