Radical C−H‐Amination of Heteroarenes using Dual Initiation by Visible Light and Iodine. Issue 20 (4th September 2018)

• Record Type: Journal Article
• Authors: Lucchetti, Nicola; Tkacheva, Anastasia; Fantasia, Serena; Muñiz, Kilian
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 20(2018)
• Page Start: 3889
• Page End: 3893
• Publication Date: 2018-09-04
• Subjects: Amination -- Amidyl Radicals -- C−H Functionalization -- Iodine -- Photochemistry; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201800677
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A novel light‐induced C−H amination of heteroarenes can be accomplished with preformed iodine(III) reagents as the combined oxidant and nitrogen source. The reaction requires the use of a small amount of molecular iodine, which under photochemical activation generates in situ an iodine(I) reagent as the initiator of the radical amination reaction. A total of 32 examples exemplify the broad scope of the transformation. Abstract :