Au3Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents. Issue 6 (19th July 2018)

• Record Type: Journal Article
• Authors: Wang, Zhiyi; Ju, Yanmin; Tong, Shiyan; Zhang, Hongchen; Lin, Jian; Wang, Baodui; Hou, Yanglong
• Is Part Of: Nanoscale horizons. Volume 3:Issue 6(2018)
• Page Start: 624
• Page End: 631
• Publication Date: 2018-07-19
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c8nh00135a
• Languages: English
• ISSNs: 2055-6756

Abstract

Abstract : Au3 Cu tetrapod nanocrystals were synthesized. After surface modification, the obtained monodisperse Au3 Cu@PEG-Cy5, FA showed great potential as a fluorescence imaging and MSOT imaging-guided photothermal agent in the NIR-II region, which could be metabolized in vitro after treatment. Abstract : Gold and gold-based alloy nanocrystals (NCs) have been widely used in the field of photothermal therapy (PTT). However, the synthesis of multimodal nano-agents for precise and efficient PTT in the second near infrared (NIR-II) region remains a great challenge. Herein, Au3 Cu TPNCs were developed as a powerful platform for multimodal image-guided photothermal therapy with significant therapeutic effects and good metabolizability in the NIR-II region.