First study on trichothecene and zearalenone exposure of the Romanian population through wheat-based products consumption. (November 2018)

• Record Type: Journal Article
• Authors: Stanciu, Oana; Juan, Cristina; Miere, Doina; Berrada, Houda; Loghin, Felicia; Mañes, Jordi
• Is Part Of: Food and chemical toxicology. Volume 121(2018)
• Page Start: 336
• Page End: 342
• Publication Date: 2018-11
• Subjects: Mycotoxins -- Fusarium -- Estimated daily intake -- Risk assessment -- Romania; 3-Acetyldeoxynivalenol (PubChem CID: 5458510) -- 15-Acetyldeoxynivalenol (PubChem CID: 3034750) -- Deoxynivalenol (PubChem CID: 40024) -- Diacetoxyscirpenol (PubChem CID: 91518) -- Fusarenon-X (PubChem CID: 304599) -- HT-2 toxin (PubChem CID: 10093830) -- Neosolaniol (PubChem CID: 13818797) -- Nivalenol (PubChem CID: 430146) -- T-2 toxin (PubChem CID: 442400) -- Zearalenone (PubChem CID: 5281576); Toxicology -- Periodicals; Food poisoning -- Periodicals; Food Poisoning -- Periodicals; Toxicology -- Periodicals; Toxicologie -- Périodiques; Intoxications alimentaires -- Périodiques; Food poisoning; Toxicology; Periodicals; Electronic journals; 615.9
• DOI: 10.1016/j.fct.2018.09.014
• Languages: English
• ISSNs: 0278-6915

Abstract

Abstract: In this study, a dietary exposure assessment of mycotoxins was conducted for the Romanian population using the contamination data of a various categories of wheat-based products for direct human consumption. Wheat-based foods (n = 181) commercialized in Romania, including flour, bread, biscuits, breakfast cereals and pasta, were evaluated by GC-QqQ-MS/MS for the occurrence of deoxynivalenol (DON), 3-acetyldeoxynivalenol (3AcDON), 15-acetyldeoxynivalenol (15AcDON), fusarenon-X, nivalenol, HT-2 and T-2 toxins, diacetoxyscirpenol, neosolaniol and zearalenone (ZEA). DON and 15AcDON were detected in 63 and 5% of all the analyzed samples, whereas 13-AcDON, HT-2, T-2, NIV and ZEA were not detected. Exposure of Romanian adult population was assessed, the EDIs for the sum of DON+3AcDON+15AcDON were 669 ng kg −1 bw day −1 at low-bound estimation, and 690 ng kg −1 bw day −1 at upper-bound estimation, being lower than the TDI set (1000 ng kg −1 bw day −1 ). Highlights: Nine trichothecenes and zearalenone content was evaluated for 181 Romanian wheat-based products. Mycotoxins exposure of Romanian adult population through wheat-based products was studied. Deoxynivalenol and 15-acetyldeoxynivalenol were detected in 114 and 10 samples, respectively. EDI value of the sum of DON+3AcDON+15AcDON for UB scenario was 69% of TDI.