In situ electrochemical polymerization of poly(3, 4-ethylenedioxythiophene) (PEDOT) for peripheral nerve interfaces. (8th August 2018)

• Record Type: Journal Article
• Authors: Murbach, Jamie M.; Currlin, Seth; Widener, Adrienne; Tong, Yuxin; Chhatre, Shrirang; Subramanian, Vivek; Martin, David C.; Johnson, Blake N.; Otto, Kevin J.
• Is Part Of: MRS communications. Volume 8:Number 3(2018)
• Page Start: 1043
• Page End: 1049
• Publication Date: 2018-08-08
• Subjects: Materials -- Periodicals; 620.11
• DOI: 10.1557/mrc.2018.138
• Languages: English
• ISSNs: 2159-6859

Abstract

Abstract: Abstract : The goal of this study was to perform in situ electrochemical polymerization of poly(3, 4-ethylenedioxythiophene) (PEDOT) in peripheral nerves to create a soft, precisely located injectable conductive polymer electrode for bi-directional communication. Intraneural PEDOT polymerization was performed to target both outer and inner fascicles via custom fabricated 3D printed cuff electrodes and monomer injection strategies using a combination electrode-cannula system. Electrochemistry, histology, and laser light sheet microscopy revealed the presence of PEDOT at specified locations inside of peripheral nerve. This work demonstrates the potential for using in situ PEDOT electrodeposition as an injectable electrode for recording and stimulation of peripheral nerves.