Dynamic constitutional frameworks for DNA biomimetic recognition. Issue 11 (11th December 2014)

• Record Type: Journal Article
• Authors: Catana, Romina; Barboiu, Mihail; Moleavin, Ioana; Clima, Lilia; Rotaru, Alexandru; Ursu, Elena-Laura; Pinteala, Mariana
• Is Part Of: Chemical communications. Volume 51:Issue 11(2015)
• Page Start: 2021
• Page End: 2024
• Publication Date: 2014-12-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc07525k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The strategy presented here can be used to self-generate dynamic constitutional networks for the systematic rationalization of active delivery systems. It leaves the possibility of DNA to self-select and self-generate the most adapted carrier for its own active and optimal transfection. Abstract : Linear and cross-linked dynamic constitutional frameworks generated from reversibly interacting linear PEG/core constituents and cationic sites shed light on the dominant coiling versus linear DNA binding behaviours, closer to the histone DNA binding wrapping mechanism.