A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats. Issue 81 (26th September 2018)

• Record Type: Journal Article
• Authors: Fu, Boshi; Park, Yoojin; Kim, Ki Tae; Chen, Kun; Zou, Guangrong; Wei, Qi; Peng, Shuang; Chen, Yuqi; Kim, Byeang Hyean; Zhou, Xiang
• Is Part Of: Chemical communications. Volume 54:Issue 81(2018)
• Page Start: 11487
• Page End: 11490
• Publication Date: 2018-09-26
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc05197f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Herein, we have developed a novel fluorescence labeling strategy for nucleic acid aptamers based on self-assembling between AGG tri-nucleotide repeats and a pyrene-modified oligonucleotide. Abstract : Herein, we have developed a novel fluorescence labeling strategy for nucleic acid aptamers based on self-assembling between AGG tri-nucleotide repeats and a pyrene-modified oligonucleotide. This strategy could be an effective tool for developing targeting–imaging systems and biosensor systems to detect target molecules.