An efficient strategy for a controllable droplet merging system for digital analysis. Issue 60 (5th October 2018)

• Record Type: Journal Article
• Authors: Qiao, Yi; Fu, Jiye; Yang, Fang; Duan, Mengqin; Huang, Mengting; Tu, Jing; Lu, Zuhong
• Is Part Of: RSC advances. Volume 8:Issue 60(2018)
• Page Start: 34343
• Page End: 34349
• Publication Date: 2018-10-05
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c8ra06022c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : We present a one-to-a-cluster pairing strategy to improve the success rate of merging under fluctuation. The one-to-a-cluster method is suitable for digital analysis and droplet MDA was performed in merged droplets successfully. Abstract : Droplet merging is an important part of droplet manipulation approaches. Droplet merging methods with expansions inside channels can merge droplets in pairs through simple structures. However, they have a low success rate of merging under unstable fluidic conditions since the one-to-one pairing strategy is sensitive to fluctuation. This study presents a one-to-a-cluster pairing strategy to improve the success rate of merging under fluctuation. The one-to-a-cluster method was suitable for digital analysis and droplet MDA was performed in merged droplets successfully.