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A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo. Issue 82 (28th September 2018)
Record Type:
Journal Article
Title:
A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo. Issue 82 (28th September 2018)
Main Title:
A ratiometric fluorescent probe for peroxynitrite prepared by de novo synthesis and its application in assessing the mitochondrial oxidative stress status in cells and in vivo
Abstract : A ratiometric fluorescent probe is prepared by de novo synthesis for assessing the mitochondrial oxidative stress status in cells and in vivo . Abstract : A ratiometric fluorescent probe Cy-NEt2 for detecting ONOO − is designed and prepared by de novo synthesis, which is a reliable, cheap and flexible route. The probe is applied for monitoring the level of mitochondrial ONOO − and assessing the lipopolysaccharide (LPS)-induced mitochondrial oxidative stress status in living cells and in vivo successfully.