Ultrasound Elastography of the Median Nerve in Patients With Acromegaly: A Case‐Control Study. (8th March 2018)

• Record Type: Journal Article
• Authors: Burulday, Veysel; Doğan, Adil; Şahan, Mehmet Hamdi; Arıkan, Şenay; Güngüneş, Aşkın
• Is Part Of: Journal of ultrasound in medicine. Volume 37:Number 10(2018)
• Page Start: 2371
• Page End: 2377
• Publication Date: 2018-03-08
• Subjects: acromegaly -- cross‐sectional area -- elastography -- peripheral nerve -- shear wave elastography -- strain elastography -- ultrasound; Ultrasonics in medicine -- Periodicals; Ultrasonics; Ultrasonography; Ultrasonics in medicine; Electronic journals; Periodicals; Periodicals; 616.07543
• DOI: 10.1002/jum.14591
• Languages: English
• ISSNs: 0278-4297

Abstract

Abstract : Objectives: The aim of this study was to compare the cross‐sectional area and ultrasound elastographic findings of the median nerve of patients with acromegaly and healthy participants. Methods: The acromegaly group comprised 15 patients with a previous diagnosis of acromegaly, and an age‐ and sex‐matched control group included healthy participants. Strain elastographic and shear wave elastographic findings and the cross‐sectional areas of the groups were compared. A 6–15‐MHz multifrequency transducer was used for ultrasound evaluations. Results: A total of 30 hands of 15 patients with acromegaly (7 male and 8 female) with a mean age ± SD of 50.00 ± 10.17 years and 40 hands of 20 healthy control participants (9 male and 11 female) with a mean age of 49.50 ± 10.17 years were taken into consideration for statistical analyses. The cross‐sectional area of the patients with acromegaly was significantly higher than that of the healthy controls (13.43 ± 3.12 versus 8.32 ± 1.94 mm 2 ; P < .05). Median nerve stiffness was significantly increased in the acromegaly group compared with the control group (axial and longitudinal, 37.15 ± 6.4 and 37.0 ± 6.19 versus 18.7 ± 4.1 and 19.2 ± 3.58 kPa, respectively; P < .001). Conclusions: These preliminary results have demonstrated that patients with acromegaly seem to have increased stiffness and cross‐sectional area of the median nerve compared with healthy participants.