Responsiveness of the ACTIVLIM‐CP questionnaire: measuring global activity performance in children with cerebral palsy. (4th June 2018)

• Record Type: Journal Article
• Authors: Paradis, Julie; Arnould, Carlyne; Thonnard, Jean‐Louis; Houx, Laëtitia; Pons‐Becmeur, Christelle; Renders, Anne; Brochard, Sylvain; Bleyenheuft, Yannick
• Is Part Of: Developmental medicine & child neurology. Volume 60:Number 11(2018)
• Page Start: 1178
• Page End: 1185
• Publication Date: 2018-06-04
• Subjects: Child development -- Periodicals; Pediatric neurology -- Periodicals; 616.8
• DOI: 10.1111/dmcn.13927
• Languages: English
• ISSNs: 0012-1622

Abstract

Abstract : Aim: To investigate the responsiveness of the ACTIVLIM‐CP questionnaire after two evidence‐based interventions for children with cerebral palsy (CP). Method: Seventy‐five children with CP either participated in an intensive motor‐skill learning intervention (hand–arm bimanual intensive therapy including lower extremities [HABIT‐ILE], n =47) or received botulinum neurotoxin‐A (BoNT‐A) injection(s) into lower extremities combined with conventional physical therapy ( n =28). All children were assessed three times: at baseline ( T 0 ; before HABIT‐ILE/the day of BoNT‐A injection), at T 1 (last day of HABIT‐ILE/6wks after BoNT‐A injection), and at follow‐up ( T 2 ; 3–4mo after the beginning of intervention). Parents completed ACTIVLIM‐CP and three other activity questionnaires. Responsiveness was analysed using group (based on intervention), subgroup (based on gross motor function level), and individual approaches. Results: For the HABIT‐ILE group, significant improvements in ACTIVLIM‐CP were observed for the T 0 – T 1 period ( p <0.001) but not for the T 1 – T 2 period. No significant changes were found in the BoNT‐A group during assessments ( p =0.84). In the subgroup analysis for the HABIT‐ILE group ( T 0 – T 1 ), greater changes were demonstrated for children in Gross Motor Function Classification System levels III and IV ( p <0.001, effect size=1.36). The individual approach was congruent with the group approach. Interpretation: ACTIVLIM‐CP demonstrated high responsiveness after HABIT‐ILE, showing that this scale may be used to investigate global activity performance in clinical trials focusing on improving daily life activities. What this paper adds: Good responsiveness of ACTIVLIM‐CP questionnaire during intensive motor‐skill learning intervention. Higher responsiveness for children in Gross Motor Function Classification System (GMFCS) levels III and IV versus I and II after intensive intervention. ACTIVLIM‐CP is useful to identify children improving their performance after botulinum neurotoxin‐A injection. What this paper adds: Good responsiveness of ACTIVLIM‐CP questionnaire during intensive motor‐skill learning intervention. Higher responsiveness for children in Gross Motor Function Classification System (GMFCS) levels III and IV versus I and II after intensive intervention. ACTIVLIM‐CP is useful to identify children improving their performance after botulinum neurotoxin‐A injection. This article is commented on by Newman on page1075 of this issue. This article's abstract has been translated into Spanish and Portuguese. Follow the links from theabstract to view the translations.