Chemical constituents from the fruiting bodies of Phellinus igniarius. Issue 20 (18th October 2018)

• Record Type: Journal Article
• Authors: Thanh, Nguyen Tan; Tuan, Nguyen Ngoc; Kuo, Ping-Chung; Dung, Doan Manh; Phuong, Doan Lan; Giang, Dinh Thi Truong; Wu, Tian-Shung; Thang, Tran Dinh
• Is Part Of: Natural product research. Volume 32:Issue 20(2018)
• Page Start: 2392
• Page End: 2397
• Publication Date: 2018-10-18
• Subjects: Phellinus igniarius -- igniarine -- Hymenochaetaceae -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1413572
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new tirucallane-type triterpenoid igniarine (1 ), and four known compounds meshimakobnol A (2 ), meshimakobnol B (3 ), ergosterol (4 ) and ergosterol peroxide (5 ), were purified from the methanol extracts of the fruiting bodies of Phellinus igniarius (DC. ex Fr.) Quél. The structure of1 was elucidated using a combination of 1D and 2D NMR techniques and HR-ESI-MS analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumour cell lines and part of the tested compounds demonstrated weak cytotoxicity. Abstract :