Lachrymal Gland Basal Cell Adenocarcinoma in a Ferret (Mustela putorius furo). Issue 2 (August 2016)

• Record Type: Journal Article
• Authors: Chambers, J.K.; Nakamori, T.; Kishimoto, T.E.; Nakata, M.; Miwa, Y.; Nakayama, H.; Uchida, K.
• Is Part Of: Journal of comparative pathology. Volume 155:Issue 2/3(2016)
• Page Start: 259
• Page End: 262
• Publication Date: 2016-08
• Subjects: basal cell adenocarcinoma -- ferret -- lachrymal gland tumour -- retinal dysplasia; Veterinary pathology -- Periodicals; Veterinary therapeutics -- Periodicals; Pathology, Comparative -- Periodicals; Therapeutics -- Periodicals; Pathology, Veterinary -- Periodicals; 636.089607
• DOI: 10.1016/j.jcpa.2016.05.015
• Languages: English
• ISSNs: 0021-9975

Abstract

Summary: A 1 cm diameter mass was detected in the caudal superotemporal area of the left eye of a 6-year-old neutered male ferret ( Mustela putorius furo ). The mass and the left eye were removed surgically. Microscopical examination revealed a tumour of the adnexal gland of the eye that had invaded the surrounding ocular muscle. The tumour was composed of basal-type epithelial cells arranged in a solid, or occasionally tubular, pattern. Immunohistochemically, the tumour cells expressed cytokeratin and p63, but not smooth muscle actin. Based on these findings, the tumour was diagnosed as a basal cell adenocarcinoma of the lachrymal gland. In addition to the tumour, the retina of the left eye was detached and folded at the centre of the globe. This is the first report of a non-human case of basal cell adenocarcinoma of the lachrymal gland. Graphical abstract: