Diterpenoid alkaloids from Aconitum vilmorinianum. (August 2015)

• Record Type: Journal Article
• Authors: Yin, Tian-Peng; Cai, Le; Fang, Hai-Xian; Fang, Yun-Shan; Li, Zhen-Jie; Ding, Zhong-Tao
• Is Part Of: Phytochemistry. Volume 116(2015:Aug.)
• Page Start: 314
• Page End: 319
• Publication Date: 2015-08
• Subjects: Aconitum vilmorinianum -- Ranunculaceae -- Diterpenoid alkaloid -- Vilmorine -- Antibacterial -- Antioxidant; Botanical chemistry -- Periodicals; Biochemistry -- Periodicals; Botany -- Periodicals; Chimie végétale -- Périodiques; 572.2
• DOI: 10.1016/j.phytochem.2015.05.002
• Languages: English
• ISSNs: 0031-9422

Abstract

Graphical abstract: Diterpenoid alkaloids, vilmorines A–D (1 –4 ), and fifteen known alkaloids were isolated from Aconitum vilmorinianum . Vilmorine A (1 ) has a unique rearranged six-membered B ring. Some isolated compounds exhibited moderate antibacterial activity and Fe 2+ chelating activity. Highlights: Diterpenoid alkaloids were isolated from A. vilmorinianum . Vilmorine A has a unique rearranged six-membered B ring. A possible biosynthetic pathway for the co-occurrence of vilmorines A–C is presented. Isolated compounds have moderate antibacterial and Fe 2+ chelating activities. Abstract: Diterpenoid alkaloids, named vilmorines A–D, in addition to fifteen known alkaloids, were isolated from roots of Aconitum vilmorinianum . Their structures were established on the basis of extensive spectroscopic analyses. Antibacterial and antioxidant studies on isolated compounds were also carried out.