'On water' direct vinylogous Henry (nitroaldol) reactions of 3, 5-dimethyl-4-nitroisoxazole with aldehydes and trifluoromethyl ketones. Issue 19 (12th May 2016)
- Record Type:
- Journal Article
- Title:
- 'On water' direct vinylogous Henry (nitroaldol) reactions of 3, 5-dimethyl-4-nitroisoxazole with aldehydes and trifluoromethyl ketones. Issue 19 (12th May 2016)
- Main Title:
- 'On water' direct vinylogous Henry (nitroaldol) reactions of 3, 5-dimethyl-4-nitroisoxazole with aldehydes and trifluoromethyl ketones
- Authors:
- Zhang, Yong
Wei, Biao-Wen
Zou, Li-Na
Kang, Mei-Lian
Luo, Hai-Qing
Fan, Xiao-Lin - Abstract:
- Abstract: An efficient 'on water'-promoted direct catalytic vinylogous addition of 3, 5-dimethyl-4-nitroisoxazole to aldehydes and trifluoromethyl ketones was described, giving Henry (nitroaldol) adducts in excellent yields. The trifluoromethyl tertiary alcohol product could be transformed to the corresponding styrene derivative, which was demonstrated as a new type of Michael acceptor in the vinylogous 1, 6-Michael addition with nitromethane. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 19(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 19(2016)
- Issue Display:
- Volume 72, Issue 19 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 19
- Issue Sort Value:
- 2016-0072-0019-0000
- Page Start:
- 2472
- Page End:
- 2475
- Publication Date:
- 2016-05-12
- Subjects:
- On water -- Vinylogous Henry reactions -- 4-Nitro-isoxazoles
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2016.03.072 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7933.xml