In situ protection methodology for selective one-pot allylation and alkylation of ketones in the presence of α, β-unsaturated ketones. Issue 19 (12th May 2016)
- Record Type:
- Journal Article
- Title:
- In situ protection methodology for selective one-pot allylation and alkylation of ketones in the presence of α, β-unsaturated ketones. Issue 19 (12th May 2016)
- Main Title:
- In situ protection methodology for selective one-pot allylation and alkylation of ketones in the presence of α, β-unsaturated ketones
- Authors:
- Watanabe, Kei
Ohta, Reiya
Morita, Kenta
Yahata, Kenzo
Minami, Masaki
Fujioka, Hiromichi - Abstract:
- Abstract: Selective one-pot alkylation or allylation of ketones in the presence of α, β-unsaturated ketones (enones) were accomplished by using our in situ protection methodology. Enones selectively react with a combination of PPh3 and silyl triflates in the presence of ketones to produce phosphonium silyl enol ethers, which act as protective groups for the enones during the alkylation or allylation of ketones, and can be easily deprotected to regenerate the parent enones on work-up. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 19(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 19(2016)
- Issue Display:
- Volume 72, Issue 19 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 19
- Issue Sort Value:
- 2016-0072-0019-0000
- Page Start:
- 2420
- Page End:
- 2428
- Publication Date:
- 2016-05-12
- Subjects:
- Enone -- Ketone -- In situ protection -- Control of the reactivity -- One-pot reaction
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2016.03.063 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7933.xml