Mycoplasma genitalium Antibiotic Resistance–Mediating Mutations in Canadian Women With or Without Chlamydia Trachomatis Infection. Issue 7 (July 2017)

• Record Type: Journal Article
• Authors: Chernesky, Max A.; Jang, Dan; Martin, Irene; Hoang, Linda M.N.; Naidu, Prenilla; Levett, Paul N.; Wylie, John; Rebbapragada, Anu; Ratnam, Sam; Smieja, Marek; Weinbaum, Barbara; Getman, Damon
• Is Part Of: Sexually transmitted diseases. Volume 44:Issue 7(2017)
• Publication Date: 2017-07
• Subjects: Sexually transmitted diseases -- Periodicals; Sexual health -- Periodicals; 616.951005
• DOI: 10.1097/OLQ.0000000000000617
• Languages: English
• ISSNs: 0148-5717

Abstract

Abstract : Abstract: Testing remnant Aptima specimens from women infected with Chlamydia trachomatis detected 13.4% (53/396) with Mycoplasma genitalium compared with 5.4% (22/406) in matched C. trachomatis –negative women. Overall, 9.4% (provincial ranges of 3–20%) were infected with M. genitalium and resistance mediating mutations were found in 47.3% (26/55) to macrolides and 1.9% (1/53) to fluoroquinolones by sequencing. Abstract : Testing remnant Aptima specimens, Mycoplasma genitalium was more often detected in Canadian women infected with Chlamydia trachomatis compared to women without Chlamydia trachomatis . Macrolide resistance mediating mutations were found in 47.3% of Mycoplasma genitalium infections.