Negative symptoms in psychometrically defined schizotypy: The role of depressive symptoms. (30th June 2016)

• Record Type: Journal Article
• Authors: Campellone, Timothy R.; Elis, Ori; Mote, Jasmine; Sanchez, Amy H.; Kring, Ann M.
• Is Part Of: Psychiatry research. Volume 240(2016)
• Page Start: 181
• Page End: 186
• Publication Date: 2016-06-30
• Subjects: Schizotypy -- Negative symptoms -- Depressive symptoms -- Motivation/pleasure -- Emotional expressivity -- Cognitive -- Somatic-affective; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2016.04.020
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: People high in schizotypy, a risk factor for schizophrenia-spectrum disorders, can have negative symptoms, including diminished experience of motivation/pleasure (MAP) and emotional expressivity (EXP). Additionally, people high in schizotypy often report elevated depressive symptoms, which are also associated with diminished MAP and EXP. In this study, we examined whether negative symptoms were related to schizotypy above and beyond the presence of depressive symptoms. Thirty-one people high in schizotypy and 24 people low in schizotypy were administered the Clinical Assessment Interview for Negative Symptoms (CAINS), an interview-based measure of MAP and EXP negative symptoms and completed a self-report measure of cognitive and somatic-affective depressive symptoms. People high in schizotypy had more MAP negative symptoms than people low in schizotypy, but we found no group differences in EXP negative symptoms. Importantly, the relationship between MAP negative symptoms and schizotypy was fully mediated by cognitive depressive symptoms. These findings suggest that depressive symptoms, specifically cognitive depressive symptoms, may be a pathway for motivation and pleasure impairment, in people at elevated risk for developing schizophrenia-spectrum disorders. Highlights: Schizotypy is associated with negative (MAP, EXP) and depressive symptoms. We sought to elucidate the relationship between these symptoms and schizotypy. The schizotypy and MAP relationship was mediated by cognitive depressive symptoms. No differences in EXP negative symptoms between people high and low in schizotypy. Cognitive depressive symptoms potential common pathway for MAP negative symptoms.