Antibacterial Effect of Bacteriocin Isolated From Lactobacillus Plantarum ATCC 8014 on Postoperative Infection of Mandibular Fracture In Vivo. Issue 3 (May 2017)

• Record Type: Journal Article
• Authors: Fu, Tao; Liu, Yan-Ming
• Is Part Of: Journal of craniofacial surgery. Volume 28:Issue 3(2017)
• Publication Date: 2017-05
• Subjects: Antimicrobial activity -- bacteriocin -- biofilm -- mandibular fracture -- mouse model -- Staphylococcus aureus; Facial bones -- Surgery -- Periodicals; Skull -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.52
• DOI: 10.1097/SCS.0000000000003469
• Languages: English
• ISSNs: 1049-2275

Abstract

Abstract : Objective: The primary objective of this study was to verify the effects of bacteriocin in treatment of postoperative infection of mandibular fracture in vivo. Methods: Eighty-two mice were inoculated intravenously with staphylococcal suspensions. Bacterial cultures were obtained from implants. Blood samples were collected at 1, 2, 4, 6, and 8 hours after the injection of bacteriocins. Results: Bacteriocins have significant inhibitory effects on Staphylococcus aureus ( P < 0.05) and there are significant differences interleukin (IL)-8 and IL-10 in serum ( P < 0.05). Conclusions: Bacteriocin isolated from L plantarum may be one of promising ways to control postoperative infection of mandibular fracture in vivo.