STERILE ENDOPHTHALMITIS AFTER INTRAVITREAL OCRIPLASMIN INJECTION: REPORT OF A SINGLE CASE. Issue Volume 9:Issues 3(2015:Summer) (2015)

• Record Type: Journal Article
• Authors: Han, Ian C.; Scott, Adrienne W.
• Is Part Of: Retinal cases & brief reports. Volume 9:Issues 3(2015:Summer)
• Publication Date: 2015
• Subjects: endophthalmitis -- intravitreal injection -- macular hole -- ocriplasmin -- uveitis -- vitreomacular adhesion; Retina -- Diseases -- Periodicals; Retina -- Periodicals; Retinal Diseases -- Periodicals; Retina -- Case Reports; Retinal Diseases -- Case Reports; 617.7
• DOI: 10.1097/ICB.0000000000000149
• Languages: English
• ISSNs: 1935-1089

Abstract

Abstract : Purpose: To report a case of presumed sterile endophthalmitis after intravitreal ocriplasmin injection. Methods: Observational case report. Review of clinical examination, ocular imaging, and published literature. Results: A 67-year-old woman with early cataracts presented with decreased vision in the left eye related to vitreomacular adhesion. She was treated with intravitreal ocriplasmin injection and developed a severe anterior chamber inflammatory reaction in less than 24 hours after the injection. Inflammation responded completely to topical steroids alone, without topical or intravitreal antibiotics. Conclusion: Patients treated with intravitreal ocriplasmin may develop an acute inflammatory reaction, which can be severe. Abstract : Sterile endophthalmitis is an uncommon complication after intravitreal injections that can present a significant diagnostic and management challenge. The authors report a case of presumed sterile endophthalmitis after intravitreal ocriplasmin injection. Physicians should be aware that patients treated with intravitreal ocriplasmin may develop an acute inflammatory reaction, which can be severe.