Anterior segment migration of dexamethasone implant: risk factors, complications, and management. Issue 3 (May 2017)

• Record Type: Journal Article
• Authors: Rahimy, Ehsan; Khurana, Rahul N.
• Is Part Of: Current opinion in ophthalmology. Volume 28:Issue 3(2017:May)
• Publication Date: 2017-05
• Subjects: anterior chamber -- complication -- corneal edema -- dexamethasone implant -- fluocinolone acetonide implant -- Iluvien -- macular edema -- migration -- ozurdex -- retisert; Ophthalmology -- Periodicals; Eye Diseases -- Indexes; Eye Diseases -- Periodicals; Review Literature -- Indexes; Review Literature -- Periodicals; Vision Disorders -- Indexes; Vision Disorders -- Periodicals; 617.7
• DOI: 10.1097/ICU.0000000000000365
• Languages: English
• ISSNs: 1040-8738

Abstract

Abstract : Purpose of review: To describe the risk factors, clinical course, and complications related to anterior segment migration of a dexamethasone (DEX) intravitreal implant, and review over potential management strategies. Recent findings: Recent reports have demonstrated that migration of a DEX implant into the anterior chamber may occur in patients with higher risk ocular characteristics. Although a relatively rare occurrence, DEX implant migration carries the possibility of inducing potentially vision-threatening corneal endothelial decompensation and edema. Summary: Any combination of previous pars plana vitrectomy, an open/defective lens capsule, and/or iris defects may increase the risk of DEX implant migration into the anterior chamber. In the setting of a DEX implant that has moved into the anterior segment with corneal edema already present, urgent removal of the implant is warranted to reduce the risk of permanent visual compromise.