FDG PET/CT in Pediatric Neurolymphomatosis. (May 2017)

• Record Type: Journal Article
• Authors: de Vaugelade, Carole; de Clermont-Gallerande, Henri; Meyer, Marie; My Duyen Tiphaine, Aude; Benjamin, Alice; Ducassou, Stephane; Chateil, Jean-François; Fernandez, Philippe
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 5(2017)
• Publication Date: 2017-05
• Subjects: bone -- large B-cell lymphoma -- metastasis -- nerve root involvement -- neurolymphomatosis -- pediatric -- PET-CT scan; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001624
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: An 8-year-old girl presented with back and leg pain and left arm and leg paresis. Lumbar puncture was suggestive of lymphocytic meningitis without identified organism. A second lumbar puncture demonstrated a large number of lymphoid B cells, with positive immunohistochemical staining for CD20 and CD25, proving the diagnosis of neurolymphomatosis. Brain and spine MRI demonstrated involvement of cervical and lumbosacral nerve roots. FDG PET/CT showed multiple bone metastases in addition to nerve involvement. Postchemotherapy FDG PET/CT demonstrated complete metabolic response.