68Ga-DOTA-TATE PET/CT for Molecular Imaging of Somatostatin Receptor Expression in Metastasizing Chordoma: Comparison With 18F-FDG. (April 2017)

• Record Type: Journal Article
• Authors: Derlin, Thorsten; Sohns, Jan M.; Hueper, Katja
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 4(2017)
• Publication Date: 2017-04
• Subjects: chordoma -- metastases -- somatostatin receptor -- octreotide -- 18F-FDG -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001576
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Chordoma is a rare slow-growing neoplasm of neuroectodermal origin, which frequently recurs after removal and has the potential to metastasize. We present the case of a 53-year-old man with metastasizing chordoma who underwent 18 F-FDG and 68 Ga-DOTA-TATE PET/CT for restaging of disease and for evaluation of targeted radionuclide therapy potential. On both 18 F-FDG and 68 Ga-DOTA-TATE PET scans, increased tracer accumulation was observed in chordoma metastases. Besides the increased glucose metabolism in chordoma, this case highlights the potential of 68 Ga-DOTA-TATE PET/CT for restaging of chordoma as well the option of targeted radionuclide therapy in this entity.