Solitary PSMA-Positive Pulmonary Metastasis in Biochemical Relapse of Prostate Cancer. (May 2017)

• Record Type: Journal Article
• Authors: Große Hokamp, Nils; Kobe, Carsten; Linzenich, Eric; Maintz, David; Drzezga, Alexander
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 5(2017)
• Publication Date: 2017-05
• Subjects: prostate cancer -- pulmonary metastasis -- prostate-specific membrane-antigen positron emission tomography -- PSA recurrence; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001582
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 63-year-old man with a history of prostate cancer, treated with resection, radiation, and androgen-depriving therapy over 4 years, was referred to our department with suspicion of recurrence based on increased blood PSA levels (1.60 ng/mL). 68 Ga PSMA PET/CT identified a solitary, PSMA-positive pulmonary nodule in the right lung. After resection, histologic analysis confirmed prostatic origin, and the blood PSA level decreased to 0.13 ng/mL. Solitary pulmonary metastasis from prostate cancer is rare. The benefits of local treatment of a single metastasis even in advanced disease are disputed among oncologists. Here, biochemical response to resection was excellent.