Prior history of testing for syphilis, hepatitis B and hepatitis C among a population-based cohort of HIV-positive individuals and their HIV-negative controls. Issue 1 (2nd January 2017)

• Record Type: Journal Article
• Authors: Shaw, Souradet Y.; Ireland, Laurie; McClarty, Leigh M.; Loeppky, Carla; Yu, Nancy; Wylie, John L.; Bullard, Jared; Van Caeseele, Paul; Keynan, Yoav; Kasper, Ken; Blanchard, James F.; Becker, Marissa L.
• Is Part Of: AIDS care. Volume 29:Issue 1(2017)
• Page Start: 67
• Page End: 72
• Publication Date: 2017-01-02
• Subjects: HIV -- serology -- public health; AIDS (Disease) -- Social aspects -- Periodicals; AIDS (Disease) -- Psychological aspects -- Periodicals; AIDS (Disease) -- Patients -- Care -- Periodicals; Acquired Immunodeficiency Syndrome; 362.1969792
• DOI: 10.1080/09540121.2016.1200715
• Languages: English
• ISSNs: 0954-0121

Abstract

ABSTRACT: Understanding patterns of serological testing for hepatitis B & C, and syphilis among HIV-positive individuals, prior to HIV diagnosis, can inform HIV diagnosis, engagement and prevention strategies. This was a population-based, retrospective analysis of prior serological testing among HIV-positive individuals in Manitoba, Canada. HIV cases were age-, sex- and region-matched to HIV-negative controls at a 1:5 ratio. Conditional logistic regression was used to examine previous serological tests and HIV status. Odds ratios (ORs) and their 95% confidence intervals (95% CI) were reported. A total of 193 cases and 965 controls were included. In the 5 years prior to diagnosis, 50% of cases had at least one test, compared to 26% of controls. Compared to those who did not have serological testing in the 5 years prior to HIV infection, those who had one serological test were at twice the odds of being HIV positive (OR: 1.9, 95% CI: 1.2–2.9), while those with 2 or more tests were at even higher odds (OR: 5.5, 95%CI: 3.7–8.4). HIV cases had higher serological testing rates. Interactions between public health and other healthcare providers should be strengthened.