Clinical features of patients with game-induced seizures in the Chinese population. (October 2016)

• Record Type: Journal Article
• Authors: Yang, Xiaoyan; Fu, Yujiao; Zhan, Qiong; Huang, Sha; Zhou, Luo; Long, Hongyu; Zhou, Pinting; Liu, Chaorong; Chen, Yayu; Long, Lili; Xiao, Bo
• Is Part Of: Seizure. Volume 41(2016)
• Page Start: 51
• Page End: 55
• Publication Date: 2016-10
• Subjects: Game-induced seizures -- Clinical features -- Chinese population; Epilepsy -- Periodicals; Epilepsy -- Periodicals; Seizures -- Periodicals; Épilepsie -- Périodiques; Electronic journals; Electronic journals; 616.853
• DOI: 10.1016/j.seizure.2016.07.003
• Languages: English
• ISSNs: 1059-1311

Abstract

Highlights: There are obvious genetic differences between patients with game-induced epilepsy. Game-induced epilepsy can be divided into two groups. One group are related to adolescent photosensitive idiopathic generalized epilepsy. Another group were adult onset, not associated with IGE, uncertain response to VPA. Abstract: Purpose: To study the clinical characteristics of patients with game-induced seizures in the Chinese population. Method: We assessed 51 patients with various game-induced epileptic seizures. Based on whether they had spontaneous seizures, these 51 patients were classified as two groups. Twenty-seven patients who had both game-induced and spontaneous seizures were referred to as Group I, whereas twenty-four patients that had experienced seizures exclusively while playing specific games were assigned to Group II. All of the related clinical data of the patients was collected and evaluated. Results: The patients in Group I presented with adolescent-onset and related to photosensitive idiopathic generalized epilepsy (IGE), were responsive to valproic acid (VPA) or magnesium valproate (VPA-Mg) therapy, and presented a major seizure-precipitating factor in response to electronic games. While patients in Group II were adult onset and not associated with IGE, showed uncertain responses to VPA and a benign prognosis, and presented major seizure-precipitating factors in response to non-electronic games. Conclusion: There are obvious genetic differences between patients with game-induced epilepsy. It is necessary to differentiate between various types of game-induced seizures and select the corresponding treatment.