Renal zoomed EPI-DWI with spatially-selective radiofrequency excitation pulses in two dimensions. Issue 10 (October 2016)

• Record Type: Journal Article
• Authors: He, Yong-Lan; Hausmann, Daniel; Morelli, John N.; Attenberger, Ulrike I.; Schoenberg, Stefan O.; Riffel, Philipp
• Is Part Of: European journal of radiology. Volume 85:Issue 10(2016)
• Page Start: 1773
• Page End: 1777
• Publication Date: 2016-10
• Subjects: DWI diffusion-weighted imaging -- z-EPI zoomed diffusion-weighted echo planar imaging -- c-EPI conventional single-shot EPI -- RF radiofrequency; Kidney -- Diffusion-weighted imaging -- Zoomed; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2016.07.022
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: Renal zoomed diffusion-weighted imaging with spatially-selective radiofrequency excitation pulses is feasible. z-EPI offers considerable potential for mitigating the limitations of conventional EPI techniques. z-EPI of kidney may lead to substantial image quality improvements with reduced artifacts. Abstract: Purpose: To evaluate the feasibility and clinical robustness of zoomed diffusion-weighted echo planar imaging (z-EPI) relative to conventional single-shot EPI (c-EPI) for DWI of the kidneys. Materials and methods: This retrospective study was approved by the institutional research ethics board. 66 patients (median age 58.5 years ± 13.4, range 23–83 years, 45 men, 21 women) undergoing 3T (Magnetom Skyra ®, Siemens Healthcare, Erlangen, Germany) using a dynamic parallel transmit array (TimTX TrueShape, Siemens Healthcare, Erlangen, Germany) for renal MRI were included in this study. Both c-EPI and z-EPI images were obtained. For z-EPI, a two-dimensional spatially-selective radiofrequency (RF) pulse was applied for echo planar imaging with the FOV reduced by a factor of 3. Two radiologists, blinded to clinical data and scan parameters evaluated the images with respect to their diagnostic confidence, overall preference, overall image quality, delineation of the kidney, spatial distortion, and image blur. Sequences were compared using a paired Wilcoxon test. ADC values for the upper pole, mid-zone, lower pole of the normal kidneys were compared between sequences as well as ADC values for renal lesions, using a paired t -test. Results: With z-EPI, the kidney was significantly better delineated with sharper boundaries, less image blur and distortion, and overall better image quality relative to c-EPI (all p < 0.001). The z-EPI technique led to greater diagnostic confidence than c-EPI (p = 0.020). z-EPI was preferred to c-EPI in 60 cases (90.9%, 60/66). No statistically significant differences in the ADC values of renal parenchyma or of renal lesions were observed between the two sequences (all p > 0.05). Conclusion: Image quality, distortion, and susceptibility artifacts might be improved by using z-EPI rather than c-EPI for DWI of the kidney.