Report of the Cent Gardes HIV Vaccines Conference. Part 1: The antibody response; Fondation Mérieux Conference Center, Veyrier-du-Lac, France, 25–27 October 2015. Issue 31 (30th June 2016)

• Record Type: Journal Article
• Authors: Girard, Marc P.; Le-Grand, Roger; Picot, Valentina; Longuet, Christophe; Nabel, Gary J.
• Is Part Of: Vaccine. Volume 34:Issue 31(2016)
• Page Start: 3557
• Page End: 3561
• Publication Date: 2016-06-30
• Subjects: HIV -- Neutralizing antibodies -- B cell lineage -- Passive immunization -- ADCC -- Mucosal immunity; Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2016.05.024
• Languages: English
• ISSNs: 0264-410X

Abstract

Abstract: The 2015 Cent Gardes Conference on HIV vaccines took place on October 25–27 at the Merieux Foundation Conference Center in Veyrier du Lac, near Annecy, France. The meeting reviewed progress in the development of HIV vaccines and identified new directions of future research. The field has advanced incrementally over the past year but major progress will require additional information from new clinical trials. In this article, we review the presentations on humoral immune responses to HIV, and highlight the difficulty of eliciting broadly neutralizing antibodies by vaccination. Advances in cellular immunity for HIV prevention will be reviewed separately, in a following article.