Enantiomeric discrimination of α-hydroxy acids and N-Ts-α-amino acids by 1H NMR spectroscopy. Issue 48 (2nd December 2015)

• Record Type: Journal Article
• Authors: Gao, Guangpeng; Lv, Caixia; Li, Qiuju; Ai, Lin; Zhang, Jiaxin
• Is Part Of: Tetrahedron letters. Volume 56:Issue 48(2015)
• Page Start: 6742
• Page End: 6746
• Publication Date: 2015-12-02
• Subjects: Enantiomeric discrimination -- α-Hydroxy acids and N-Ts-α-amino acids -- 1H NMR spectroscopy; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.10.060
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: A new kind of chiral compounds with multiple amino, amido and phenolic hydroxy groups has been synthesized fromd -phenylalanine andd -phenylglycine, respectively. The enantiomeric discriminations of α-hydroxy acids and N -Ts-α-amino acids have been finished in the presence of the above chiral compounds as chiral solvating agents by 1 H NMR spectroscopy. The results show that the chiral compounds are highly effective and practical chiral solvating agents towards α-hydroxy acids and N -Ts-α-amino acids.