Carbamazepine Toxicity–Induced Spindle Coma: A Novel Case Report. Issue 2 (March 2017)

• Record Type: Journal Article
• Authors: Chauhan, Bhumir; Patanvadiya, Amitkumar; Dash, Gopal Krishna
• Is Part Of: Clinical neuropharmacology. Volume 40:Issue 2(2017)
• Publication Date: 2017-03
• Subjects: carbamazepine -- hemodialysis -- overdose -- spindle coma; Neuropharmacology -- Periodicals; 615.78
• DOI: 10.1097/WNF.0000000000000206
• Languages: English
• ISSNs: 0362-5664

Abstract

Abstract : Abstract: A 9-year-old girl presented with alleged history of deliberate ingestion of 4 g of carbamazepine, following which she became comatose. A bedside electroencephalogram (EEG) was performed to rule out nonconvulsive status epilepticus, which showed presence of spindle coma (SC), not reactive to noxious stimuli. Following hemodialysis, a second EEG showed absence of SC and complete clinical recovery. We present this unique case of carbamazepine-induced SC, thereby highlighting the extent of the etiologic spectrum of SC and discussing the literature related to this association.