Co-immobilization of chitosan and dermatan sulfate from Raja montagui skin on polyethylene terephthalate surfaces: Characterization and antibiofilm activity. Issue 5 (24th March 2018)

• Record Type: Journal Article
• Authors: Hayder, Jihane; Chaouch, Mohamed Aymen; Amira, Noumi; Ben Mansour, Mohamed; Majdoub, Hatem; Chaubet, Frédéric; Maaroufi, Raoui Mounir
• Is Part Of: International journal of polymeric materials. Volume 67:Issue 5(2018)
• Page Start: 277
• Page End: 287
• Publication Date: 2018-03-24
• Subjects: Antibiofilm -- chitosan -- dermatan sulfate -- material -- polyethylene terephthalate -- Staphylococcus epidermidis -- surface modification; Polymers -- Periodicals; Plastics -- Periodicals; 620.19205
• DOI: 10.1080/00914037.2017.1320664
• Languages: English
• ISSNs: 0091-4037

Abstract

ABSTRACT: In this work, polyethylene terephthalate (PET) was chemically modified by covalent co-immobilization of two separate layers of bioactive polymers composed of chitosan and a new dermatan sulfate isolated from Raja montagui skin. The new materials obtained were characterized by determination of carboxyl groups, ATR-FTIR spectroscopy, drop water contact angle, SEM, and TGA measurements. The different immobilizations modified the surface characteristics; especially when the first layer was dermatan sulfate (PET–DS–Chito) which presented the best surface wettability (71 ± 3°). It also reduced the ability of Staphylococcus epidermidis to form biofilm on PET surfaces which could decrease the virulence of vascular prosthesis infections. GRAPHICAL ABSTRACT: