Fatal case of hemolytic-uremic syndrome in an adult due to a rare serogroup O91 Entero hemorrhagic Escherichia coli associated with a Clostridium difficile infection. More than meets the eye. (August 2015)

• Record Type: Journal Article
• Authors: Guillard, Thomas; Limelette, Anne; Le Magrex-Debar, Elisabeth; Wynckel, Alain; Gouali, Malika; Mariani-Kurkdjian, Patricia; Guyot-Colosio, Charlotte; de Champs, Christophe
• Is Part Of: International journal of infectious diseases. Volume 37(2015:Aug.)
• Page Start: 113
• Page End: 114
• Publication Date: 2015-08
• Subjects: Hemolytic Uremic Syndrome -- Escherichia coli -- Clostridium difficile; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2015.06.015
• Languages: English
• ISSNs: 1201-9712

Abstract

Highlights: To our knowledge, O91 HUS cases are poorly reported in literature. We report here a case of post-diarrheal HUS due to EHEC O91 in an elderly patient in whom diagnosis was delayed given the C. difficile infection previously diagnosed. This case highlights the usefulness of Shiga-toxin detection. EHEC detection in children and adults with bloody diarrhea is a major public health issue because it will help to increase epidemiological knowledge about non-O157 infection and prophylactic and therapeutic management of severe complications such as HUS. Abstract: Hemolytic-uremic syndrome due to enterohemorrhagic Escherichia coli, belonging to serogroup O91 has rarely been described. We report here a case of post-diarrheal HUS due to EHEC O91 in an elderly patient for whom diagnosis was delayed given a previously diagnosed C. difficile infection. This case highlights the usefulness of Shiga-toxin detection.