The development of non-coding RNA ontology. (2016)

• Record Type: Journal Article
• Authors: Huang, Jingshan; Eilbeck, Karen; Smith, Barry; Blake, Judith A.; Dou, Dejing; Huang, Weili; Natale, Darren A.; Ruttenberg, Alan; Huan, Jun; Zimmermann, Michael T.; Jiang, Guoqian; Lin, Yu; Wu, Bin; Strachan, Harrison J.; Silva, Nisansa De; Kasukurthi, Mohan Vamsi; Jha, Vikash Kumar; He, Yongqun; Zhang, Shaojie; Wang, Xiaowei; Liu, Zixing; Borchert, Glen M.; Tan, Ming
• Is Part Of: International journal of data mining and bioinformatics. Volume 15:Number 3(2016)
• Page Start: 214
• Page End: 232
• Publication Date: 2016
• Subjects: non-coding RNA -- ncRNA -- bio-ontologies -- domain ontology -- reference ontology -- ontology development -- semantic data annotation -- bioinformatics; Data mining -- Periodicals; Bioinformatics -- Periodicals; 006.312
• Languages: English
• ISSNs: 1748-5673

Abstract

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.