Nitric oxide‐cold stress signalling cross‐talk, evolution of a novel regulatory mechanism. Issue 12 (17th May 2013)

• Record Type: Journal Article
• Authors: Sehrawat, Ankita; Gupta, Ravi; Deswal, Renu
• Is Part Of: Proteomics. Volume 13:Issue 12/13(2013:Jun.)
• Page Start: 1816
• Page End: 1835
• Publication Date: 2013-05-17
• Subjects: Cold stress responsive proteins -- Nitration -- Plant proteomics -- S‐Glutathionylation -- S‐nitrosylation; Proteins -- Separation -- Periodicals; Bioinformatics -- Periodicals; Proteomics -- Periodicals; Genomes -- Periodicals; Molecular genetics -- Periodicals; 572.605
• DOI: 10.1002/pmic.201200445
• Languages: English
• ISSNs: 1615-9853

Abstract

Abstract : Plants enhance their cold stress tolerance by cold acclimation, a process which results in vast reprogramming of transcriptome, proteome and metabolome. Evidence suggests nitric oxide (NO) production during cold stress which regulates genes (especially the C‐repeat binding factor (CBF) cold stress signalling pathway), diverse proteins including transcription factors (TFs) and phosphosphingolipids. About 59% (redox), 50% (defence/stress) and 30% (signalling) cold responsive proteins are modulated by NO‐based post translational modifications (PTMs) namely S‐nitrosylation, tyrosine nitration and S‐glutathionylation, suggesting a cross‐talk between NO and cold. Analysis of cold stress responsive deep proteome in apoplast, mitochondria, chloroplast and nucleus suggested continuation of this cross‐talk in sub‐cellular systems. Modulation of cold responsive proteins by these PTMs right from cytoskeletal elements in plasma membrane to TFs in nucleus suggests a novel regulation of cold stress signalling. NO‐mediated altered protein transport in nucleus seems an important stress regulatory mechanism. This review addresses the NO and cold stress signalling cross‐talk to present the overview of this novel regulatory mechanism.