Depressive Symptoms: Mediator of Event-Free Survival in Patients With Heart Failure. (April 2017)

• Record Type: Journal Article
• Authors: Hammash, Muna H.; Lennie, Terry A.; Crawford, Timothy; Heo, Seongkum; Chung, Misook L.; Biddle, Martha J.; Dekker, Rebecca; Wu, Jia-Rong; Rayens, Mary Kay; Moser, Debra K.
• Other Names: Moser Debra K. guest-editor.
• Is Part Of: Western journal of nursing research. Volume 39:Number 4(2017)
• Page Start: 539
• Page End: 552
• Publication Date: 2017-04
• Subjects: health perceptions -- event-free survival -- depressive symptoms -- heart failure -- mediation; Nursing -- Research -- Periodicals; Nursing -- Periodicals; Nursing -- Research -- West (U.S.) -- Periodicals; Nursing -- West (U.S.) -- Periodicals; Nursing -- Periodicals; Nursing Research -- Periodicals; Soins infirmiers -- Recherche -- Périodiques; Soins infirmiers -- Périodiques; Soins infirmiers -- Recherche -- États-Unis (Ouest) -- Périodiques; Soins infirmiers -- États-Unis (Ouest) -- Périodiques; Soins infirmiers; Recherche; États-Unis (Ouest); Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 610.730702
• DOI: 10.1177/0193945916658883
• Languages: English
• ISSNs: 0193-9459

Abstract

Depressive symptoms and poor health perceptions are predictors of higher hospitalization and mortality rates (heart failure [HF]). However, the association between depressive symptoms and health perceptions as they affect event-free survival outcomes in patients with HF has not been studied. The purpose of this secondary analysis was to determine whether depressive symptoms mediate the relationship between health perceptions and event-free survival in patients with HF. A total of 458 HF patients (61.6 ± 12 years, 55% New York Heart Association Class III/IV) responded to one-item health perception question and completed the Patient Health Questionnaire–9. Event-free survival data were collected for up to 4 years. Multiple regression and Cox proportional hazards regression analysis showed that depressive symptoms mediated the relationship between health perceptions and event-free survival. Decreasing depressive symptoms is essential to improve event-free survival in patients with HF.