Managing the Female Patient with Hereditary Angioedema. (June 2016)

• Record Type: Journal Article
• Authors: Banerji, Aleena; Riedl, Marc
• Is Part Of: Women's health. Volume 12:Number 3(2016)
• Page Start: 351
• Page End: 361
• Publication Date: 2016-06
• Subjects: C1-inhibitor -- ecallantide -- hereditary angioedema -- icatibant -- women; Gynecology -- Periodicals; Obstetrics -- Periodicals; Women -- Health and hygiene -- Periodicals; 618.05
• DOI: 10.2217/whe.16.6
• Languages: English
• ISSNs: 1745-5057

Abstract

Hereditary angioedema (HAE) is a rare disorder resulting from decreased functional levels of C1 -inhibitor (C1-INH), which manifests as periodic episodes of localized edema which can be extremely painful, debilitating and even fatal if the swelling affects the larynx. HAE can complicate many aspects of obstetric/gynecologic care, and an awareness of the disease is critical for clinicians involved in the care of women because of potential HAE-related complications pertaining to pregnancy, labor and delivery, and other women's health issues. This article provides a review of published literature specific to HAE and its management in female patients, including important concerns regarding obstetric/gynecologic care. A growing body of relevant experience is presented to help guide the care of women with HAE.