Women and Functional Dyspepsia. (March 2016)

• Record Type: Journal Article
• Authors: Napthali, Kate; Koloski, Natasha; Walker, Marjorie M; Talley, Nicholas J
• Is Part Of: Women's health. Volume 12:Number 2(2016)
• Page Start: 241
• Page End: 250
• Publication Date: 2016-03
• Subjects: functional dyspepsia -- Helicobacter pylori -- prokinetics -- proton pump inhibitors; Gynecology -- Periodicals; Obstetrics -- Periodicals; Women -- Health and hygiene -- Periodicals; 618.05
• DOI: 10.2217/whe.15.88
• Languages: English
• ISSNs: 1745-5057

Abstract

Functional dyspepsia is relatively common yet poorly understood. The best accepted diagnostic criteria are the Rome III criteria. The epidemiology, healthcare seeking rates, impact and pathophysiology are reviewed with a focus on women. Treatment is limited with no clearly established regimen currently recommended. Duodenal eosinophilia may be found in a subset. Proton pump inhibitors and prokinetic agents represent the standard therapeutic regimen after Helicobacter pylori infection has been eliminated. Some novel agents such as the prokinetic acotiamide appear promising; however, the need for a safe and efficacious treatment remains largely unmet. This review also describes the currently available management options for functional dyspepsia.