Percutaneous pharmacomechanical thrombectomy for acute iliofemoral deep vein thrombosis: A suitability study. (May 2015)

• Record Type: Journal Article
• Authors: Nghiem, AZ; Rudarakanchana, N; Moore, HM; Davies, AH
• Is Part Of: Phlebology. Volume 30:Number 4(2015)
• Page Start: 235
• Page End: 241
• Publication Date: 2015-05
• Subjects: Deep vein thrombosis -- post-thrombotic syndrome -- thrombectomy -- thromboembolism -- ulcer; Veins -- Diseases -- Periodicals; 616.14
• DOI: 10.1177/0268355514521607
• Languages: English
• ISSNs: 0268-3555

Abstract

Objectives: Percutaneous pharmacomechanical thrombectomy is an emerging therapy for acute deep vein thrombosis and may reduce long-term incidence of post-thrombotic syndrome. This study investigates the proportion of patients presenting with lower limb deep vein thrombosis who are potentially suitable for percutaneous pharmacomechanical thrombectomy. Methods: A retrospective review of all duplex ultrasound scans for lower limb deep vein thrombosis over two-year period at a regional vascular unit was conducted. All acute occlusive iliofemoral deep vein thrombosis were screened for percutaneous pharmacomechanical thrombectomy suitability according to predefined criteria. Results: There were 2513 duplex ultrasound scans for suspected lower limb deep vein thrombosis in the two-year period. There were 120 cases of acute occlusive iliofemoral deep vein thrombosis. After application of inclusion and exclusion criteria 48 out of 120 (40%) patients were identified as potential candidates for percutaneous pharmacomechanical thrombectomy. Conclusions: This indicates that a large randomised trial of percutaneous pharmacomechanical thrombectomy is feasible given expected recruitment rates in a multicentre study.