Emerging indications of endoscopic radiofrequency ablation. Issue 4 (August 2015)

• Record Type: Journal Article
• Authors: Becq, Aymeric; Camus, Marine; Rahmi, Gabriel; de Parades, Vincent; Marteau, Philippe; Dray, Xavier
• Is Part Of: United European Gastroenterology journal. Volume 3:Issue 4(2015:Aug.)
• Page Start: 313
• Page End: 324
• Publication Date: 2015-08
• Subjects: Radiofrequency -- esophageal neoplasia -- gastrointestinal bleeding -- radiation proctopathy -- biliary strictures; Gastroenterology -- Periodicals; Periodicals; 616.33005
• DOI: 10.1177/2050640615571159
• Languages: English
• ISSNs: 2050-6406

Abstract

Introduction: Radiofrequency ablation (RFA) is a well-validated treatment of dysplastic Barrett's esophagus. Other indications of endoscopic RFA are under evaluation. Results: Four prospective studies (total 69 patients) have shown that RFA achieved complete remission of early esophageal squamous intra-epithelial neoplasia at a rate of 80%, but with a substantial risk of stricture. In the setting of gastric antral vascular ectasia, two prospective monocenter studies, and a retrospective multicenter study, (total 51 patients), suggest that RFA is efficacious in terms of reducing transfusion dependency. In the setting of chronic hemorrhagic radiation proctopathy, a prospective monocenter study and a retrospective multicenter study (total 56 patients) suggest that RFA is an efficient treatment. A retrospective comparative study (64 patients) suggests that RFA improves stents patency in malignant biliary strictures. Conclusions: Endoscopic RFA is an upcoming treatment modality in early esophageal squamous intra-epithelial neoplasia, as well as in gastric, rectal, and biliary diseases.