Nonenzymatic multispecies sensor based on Cu-Ni nanoparticle dispersion on doped graphene. (10th January 2017)

• Record Type: Journal Article
• Authors: Shabnam, Luba; Faisal, Shaikh Nayeem; Roy, Anup Kumar; Minett, Andrew I.; Gomes, Vincent G.
• Is Part Of: Electrochimica acta. Volume 224(2017)
• Page Start: 295
• Page End: 305
• Publication Date: 2017-01-10
• Subjects: nonenzymatic sensor -- doped graphene -- Cu-Ni nanoparticle -- glucose -- hydrogen peroxide; Electrochemistry -- Periodicals; Electrochemistry, Industrial -- Periodicals; 541.37
• DOI: 10.1016/j.electacta.2016.12.056
• Languages: English
• ISSNs: 0013-4686

Abstract

Graphical abstract: Highlights: Developed a sensitive nonenzymatic high precision glucose/H2 O2 sensor. Catalytic activity via synergetic effect of doped graphene with copper and nickel. Excellent non-interference, stability, reproducibility and detection limit. Simultaneously detected glucose and H2 O2 in human urine samples. Abstract: A non-enzymatic sensing platform was developed for detecting glucose and hydrogen peroxide using nitrogen doped graphene decorated with copper-nickel nanoparticles. The synthesized CuNi-NGr composite presented excellent electrocatalytic interaction with glucose and hydrogen peroxide owing to the synergistic effect of copper, nickel and N-graphene. The enhanced performance of the active materials was due to the presence of nitrogen based active sites with high contents in pyridinic and graphitic N as well as the electrocatalytic activity of distributed copper and nickel nanoparticles on graphene. Amperometric analysis showed that the sensitivity of CuNi-NGr based electrode was 7143 μA.mM −1 .cm −2 at low (0.01 μM to 1 mM), and 1030 μA.mM −1 .cm −2 at high concentrations (2 to 20 mM) of glucose. The detection responses had corresponding linear ranges as functions of concentration with limit of detection (LOD): 10 nM at S/N = 3. For hydrogen peroxide, the fabricated electrode showed detection sensitivity of 954 μA.mM −1 .cm −2 with LOD of 10 μM (S/N = 3) and linear response within 0.01 to 1 mM. On testing, the electrode displayed excellent reproducibility, stability and selectivity for detecting glucose and H2 O2 simultaneously in aqueous electrolytes. The sensor was shown to be effective in analyzing glucose and H2 O2 present in human urine with excellent recovery.